Showing posts with label journal of complementary Medicine. Show all posts
Showing posts with label journal of complementary Medicine. Show all posts

Saturday, 16 September 2023

Lupine Publishers | A Control Study of Calligraphy Training Plus Drug Treatment in The Intervention of Anxiety Disorder

 Lupine Publishers | Journal of Complementary & Alternative Medicine


Abstract

Background: Chinese calligraphy handwriting (CCH) enhances one’s cognitive, emotional, and physiological functions. Its applications have shown effective improvements in psychological, psychosomatic, behavioral, and clinical disorders, including anxiety symptoms associated with neurosis, depression, schizophrenia, and cancers.

Objectives: We tested the effects of a combined CCH plus Venlafaxine training as a new treatment method, which involved the use of anti-anxiety drugs together with CCH training for a new system of behavioral intervention.

Methods: 60 patients meeting the criterion of CCMD-3 for anxiety disorder were assigned randomly to the Exp Group (N-31) or the Control Group (N-29) for an eight-week protocol. The Exp Group was given both Venlafaxine and the CCH training, whereas the Control Group received only Venlafaxine. Effects were evaluated with the Hamilton Anxiety Scale (HAMA), Self-Rating Anxiety Scale (SAS), and Clinical Global Impression Scale (CGI) before and after 2, 4, 8 weeks of treatment, respectively.

Results: The Total Scores of HAMA, SAS, CGI in the Exp Group showed significant improvements after 4 and 8-weeks of the treatment (p<.05). All Pre-Post t-tests for the Exp Group in all three measures reached P<0.01 level, whereas those for the Control Group reached P<0.05 level of significance, both after the 8th week. postt-tests after the 4th week showed P<0.05 for the Exp Group, but not for the Control Group in any of the measures.

Conclusion: Treatment by CCH plus Venlafaxine resulted in better effects than using only Venlafaxine for anxiety disorders. The combined drug and CCH intervention offers effective clinical outcomes

Background

Anxiety disorder, i.e., anxiety neurosis, includes generalized anxiety disorder, panic disorder, social anxiety disorder (social phobia), and various phobia-related disorders. One can have more than one anxiety disorder. Sometimes anxiety results from a medical condition that needs treatment. Anxiety disorders are generally treated with cognitive behavior therapy (CBT), antianxiety medication as well as stress management techniques, including meditation and biofeedback. Several Chinese medical practices of acupuncture, Qigong, Taiqi and calligraphy training have shown positive effects on anxiety and depression Xu, et.al. [1]. Chinese calligraphy handwriting (CCH) enhances one’s cognitive, emotional, and physiological functions Kao, [2,3]. Its applications in behavioral, psychosomatic, and cognitive disorders have shown positive improvements, including anxiety symptoms in patients with schizophrenia Fan, et.al. [4]. neurosis Kao, et.al. [5]. and depression Kao, et.al. [6]. and PTSD Zhu, et. al. [7]. In addition, similar states of anxiety and profiles of moods have also been investigated on patients with breast cancer Liu, et.al. [8], Nasopharyngeal Carcinoma cancer Yang, et.al. [9]. as well as conditions of depression associated with cancer patients in a scoping review Wagner, et.al. [10] A recent study of World Health Organization (WHO) has identified and praised our CCH therapy as an effective treatment of stress and anxiety conditions and behavioral change of the childhood survivors of the massive 2018 Sichuan Earthquakes Foucourt et.al. [11].

Above all, a series of brain imaging studies have provided encouraging evidence of the CCH’s varied training effects and influences on the practitioner from a fundamental neuroscience perspective. One study using fMRI technique has found that longterm CCH training may be associated with improvements in specific aspects of executive functions and strengthened neural networks in related brain regions Chen W, et.al. [12]. Another recent VBM study suggested that CCH training may improve attention and influence brain structures through mental processes such as meditation Chen W, et.al. [13]. These research studies provided theoretical support to the clinical effects of calligraphy training for clinical application in the present study. No direct comparisons on treatment effects between calligraphy training and drug treatment have been attempted in the past dealing with any psycho-emotional disorders. Thus, the present study explored the therapeutic effects of calligraphy training plus Venlafaxine on patients with anxiety disorder, testing the efficacy of both the anti-anxiety drug and a calligraphy-based behavioral intervention.

Method

Participants

Sixty patients who met the criterion of CCMD-3 for anxiety disorder participated in the study. They were outpatients or inpatients of Binzhou Mental Health Center from March 2003 to March 2005. All of them had a HAMA (Hamilton Anxiety Scale) score not lower than fifteen and an SAS (Self-Rating Anxiety Scale) score not lower than fifty. They had neither serious physical diseases nor serious suicidal tendencies. Participants were assigned randomly to experimental group or control group treatment based on their visit consequence. The study group was given venlafaxine in addition to calligraphy training while the control group was given venlafaxine only. In the experimental group, there were 31 patients with an average age of 32.4±7.8 years and an average span of disease 15.4 ±12.8 months, with 13 male and 18 female, 10 outpatients and 21 inpatients. Another 29 patients were in the control group, consisting of 14 male and 15 female, 9 outpatients and 20 inpatients. The average age was 30.5±8.6 years and the average span of disease was 16.4±10.7 months. Patients in both groups had educational levels above junior secondary school. Comparisons of the two groups based on any aspect mentioned above attain no significance both for the Chi-square test and for the T-test (p >.05).

Procedure

Drug therapy: After a two-week washout period, all the participants were given venlafaxine, with a dose of 50 mg/d at the beginning and adding to 200-250 mg/d within 2-3 weeks accordingly. The medicine was taken fifteen minutes after breakfast and after supper. Calligraphy training: In addition to the Venlafaxine, patients in the experimental group had calligraphy training five times a week for a period of eight weeks, for two hours per session. Calligraphy training was explained and directed by two disciplined psychiatrists and two nurses in the Handwriting and Painting Room, to ensure that the participants understood the training objectives, meanings, and the operation methods as well. Participants were asked to write characters of varying levels of difficulty. For the inpatients, we examined and kept track of their training completion status as well as their emotional regulation. For the outpatients, we did not offer any instructions at any time, so we gave them calligraphic assignments according to their actual situation, asking them to perform calligraphy handwriting for two hours every day and have subsequent visit every week. We asked about their disease progress in the past week and regularly evaluated their calligraphic writing and shared the experience of calligraphic handwriting. During the process of calligraphic writing, the participants established consciousness of self-control and relieved anxiety emotion by developing an interest in calligraphy.

Treatment Evaluation HAMA, SAS and CGI (Zhang, 2001) were used as indications in the evaluation of treatment effects, and they were evaluated by two associate chief physicians (the Kappa test for consistency equals to .89). Participants were administered these tests before treatment and 2, 4, 8 weeks after the beginning of the treatment. Three patients in the experimental group and two patients in the control group dropped out, and their absence did not cast influence on the statistical results for either the experimental or control group. Clinical effects were assessed in four grades according to the HAMA score-reduction rate: >75% -clinical recovery; 50%-75% -significant progress; 25%-49%-improve; <25%- no effect (Zhou & He, 2005). The first three grades were marked effective.

Results

The comparisons of clinical effects of CCH treatment between the experimental group and control group are provided in the Table 1 below. Results showed that the effective rates of 2-, 4-, and 8-weeks’ treatment in the experimental group were 28.5%, 57.1% and 71.4% respectively while corresponding rates were 14.8%, 29.6% and 44.4% in the control group. Chi-square test showed the differences of the two groups were significant, indicating calligraphy training plus Venlafaxine was more effective than merely venlafaxine therapy in the treatment of anxiety disorder. The comparisons between pre-and post- CCH treatment effects in HAMA, SAS and CGI of the two groups are given below. Results indicate that pretreatment comparisons of the two groups in HAMA, SAS and CGI-SI were non-significant (p>. 05). After 4-week and 8-week treatments, HAMA, SAS and CGI-SI scores in experimental group decreased significantly compared with those of pre-treatment (p<.05 or p<.01); in the control group, the drug therapy only took effect after an 8-week treatment (p<.05). Between-group comparisons of 4-week and 8-week post-treatment tests also showed significant differences between experimental group and control group. These results demonstrated a more rapid and greater improvement when the patients also proceed with calligraphy training besides antianxiety drugs treatment.

Table 1: comparison within group a p<.05, b p<.01; Comparisons between groups c p<.05.

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Discussions

Long-term calligraphy training brings practitioners into a composed, stable, and tranquil state, helping them to relieve from anxiety and emotional tension and to maintain physical and mental health Kao, [1]. Abundant evidence has showed that calligraphy handwriting has positive effects in assisting our brain in achieving a state of intense concentration, in regulating our emotions as well as antagonistic system Kao et.al. [3]. When performing calligraphy, practitioners are concentrated in performing control writing activities and try to reduce influence from environment so that they can easily enter a state of tranquility and relaxation. Such a stable and relaxed states enable anxiety patients to reduce the bias of attention which makes them selectively pay attention to those closed to depressed emotion. This is a diversion of attention, helping the anxiety patients to focus less on things that lead to fears and anxiety Kao,[14]. There are studies investigating the relation between calligraphy practice and emotional response. They have provided firm evidence to show effects of calligraphy in helping practitioners to regulate their emotion by changing and adjusting their respiration, heart rate and blood pressure Kao,[13]. Huang and his colleagues Kao,[13]. found that there were significant differences between people with calligraphy experience and those without in terms of self-report symptom inventory, and those with long-term calligraphic experience possessed better mental health. Additionally, calligraphy practice has obviously positive effects in fear reaction Luo, et.al. [15]. Luo et al [14] found that under intense working environments, practicing calligraphy for half an hour every day for one month can reduce positive symptoms, relive emotional tension, and help to regulate emotion [Table 2].

Table 2: comparison with pre-treatment, a p<.05, b p<.01; Comparisons between groups c p<.05.

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Results of the present study indicate that the experimental group has more rapid and greater effect in anxiety reduction than the control group. In addition, patients’ subjective experience was better when practicing calligraphy. For example, some patients said they were able to concentrate their attention and empty out all other thoughts from their mind, they had stable emotion and good mood, and that they felt emotional relief after calligraphy training. Though the sample was not large, we can see that calligraphy training can significantly improve state of depression and anxiety in the short term, so as to reduce anxiety symptoms and bolster the effects of drugs. These results are consistent with those reported by Calligraphy practice can be quite easy and convenient, since it can be carried out out at home to facilitate physical and mental health and reduce recurrence rate of diseases. Short-term treatment and observation is far from enough to evaluate the effects of any therapy method. We need to proceed with long-term follow up interventions, to grasp patients’ state of mind and give psychological consulting based on an overall consideration of various factors. It is a process of remolding personality, optimizing the environment, and a process full of difficulty and hardship. Further exploration is needed for influence of factors, such as patients’ personality, families, and social environment on the effects of treatment.

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Friday, 16 June 2023

Lupine Publishers | Calligraphic Handwriting (CCH) Effects on Moods and Anxiety of Type II Diabetes Patients

 Lupine Publishers | Journal of Complementary & Alternative Medicine


Abstract

Background

Chinese Calligraphic Handwriting (CCH), a WHO (2019) recognized effective treatment, enhances our cognitive abilities, relaxed bodily conditions and stabilized emotions. It has successfully treated the emotion-related anxieties and the moods that are associated with several diseases and disorders. The present study tested this intervention on Diabetes patients.

Method

16 type II diabetes patients and 16 healthy subjects participated. Each group performed both the CCH tasks of brush handwriting of Chinese characters and the brush drawing of geometric patterns. The Chinese versions of STAI and POMS measured the effects of brush writing and brush drawing tasks. on the participants. Both scales were administered to all participants before and after a 40-minute training session.

Findings

The patients group significantly improved on Pre-Post measures of the STAI in both the brush writing (F= 11.97; p=0.004) and brush drawing (F=14.08, p=0.002) tasks. However, the healthy subjects group also showed similarly a pre-post significant effects on the STAI scores from the brush writing (F = 32.02; p = 0.000) and the drawing tasks (F= 14.05, p=0.002).

Moreover, both groups showed a significant reduction in the postforms states of Tension-Anxiety, Depressed-Dejection and Confusion-Bewilderment in the brush writing task (P<0.001), but only Tension-Anxiety and Depressed-Dejection in the brush drawing tasks (P<0,001), The reduction in each case from the patient groups is greater than that from the healthy subject’s group (0.001).

Interpretation

The Brush Writing and Brush Drawing as treatments have shown significant improvements in STAI and some POMS states of the practicing Type II diabetes patients.

Chinese Calligraphy

Chinese handwriting, especially with a brush, can be conceptualized as an act involving the whole body of the writer in which cognitive planning, organizing, and processing of visualspatial patterns of the character take place. Motor control and maneuvering of the brush following the character configurations involve the whole body projected relative to the geometry of each character. The activity of brush writing is essentially an external projection and execution of the writer’s internal cognitive images of the character. There is therefore an integration of mind, body, and character interwoven in the dynamic calligraphic process. The heritage of Chinese calligraphy is traditionally used to enhance an individual’s self-reflection and cultivation.

Our research in the past 30 years has identified five dimensions of beneficial behavior arising from the practice of Chinese calligraphy handwriting (CCH). These are visual attention, cognitive activation, physiological slowdown, emotional relaxation and behavioral change and development Kao [1]. These findings have contributed significantly to the improvement of the practitioner’s psychological health and wellbeing.

Chinese characters have different visual geometric properties. Some characters are extremely detailed and require several strokes (Fly, dragon) while some other characters are symmetrical (South, grass) some are parallel (Wang, book. Of course, there are also characters that are neither asymmetrical nor parallel (Heart, Yao).

Directional characters possess character forms of shapes that orient upwards, downwards, to the right or to the left (Mountain, dry). Some characters have strokes that are closely linked together as a unit (Foot, Shen); characters without such features are nonconnected characters (Small, swimming). Closed characters have enclosed or holes in the construction (Crystal, vessel) and the nonclosed characters do not have these features (Than, coincidence). We have found that these visual-spatial variations of the characters have a powerful impact on the practitioner’s writer’s bodily and psycho-emotional states during dynamic calligraphic execution.

Effects of Calligraphy Training

Cognitive Effects

The practice of Chinese calligraphic training has been confirmed to facilitate and increase some cognitive changes. Cognitive changes associated with CCH practice include such intellectual abilities as Spatial Ability, Abstract Reasoning, Short-term Memory, Picture Memory, and cognitive Reaction Time Kao [2] as well as cognitive and perceptual tasks such as visual and auditory attention, concentration, and spatial reasoning Kao [3].

Physiological and Cognitive Neural Effects

Some of the psychological effects studied over the years have included reduced heart rate, blood pressure, skin conductance, raised skin temperature, slower respiration, and relaxed muscular tension. This calligraphic impact has also been confirmed for attention and emotional stability and mental relaxation Kao et.al. [4]. In addition, recent brain-imaging studies have further confirmed the CCH training and practice effects on shaping the structure and functions of the brain Xu et.al. [5]; Chen et al. [6] and better executive functions and stronger resting-state functional connectivity in related brain regions Chen et al. [7]. These findings provide powerful confirmation of CCH’s impact on the brain’s cognitive neural dimensions of the practicing calligraphers.

Bio-emotional Effects

The direct outcome of such changes as well as the overall physical quiescence evokes sensory feedback: states of emotional relaxation, calmness, tranquility, and peace of the mind, which offers a psychological incentive for further motor control and execution of the brushing acts. In other words, the reason for continuing is due to the physiological slowdown as well as the soothing and relaxing states of emotions Kao, 2006; Kao [8]; (Kao, Zhu, Chao, Chen, Lie & Zhang, 2014). Our recent study on CCH training effects on HRV coherence increase is another evidence of its effectiveness Lam et.al. [9].

Foundations of CCH Treatment on Emotional States of Diabetes

We know that diabetes can cause a wide array of complications, which would exert great influence on diabetic patients’ emotions and increased stress. Anxiety and depression are common occurrences among these patients and often debilitate them Karlsen et.al.[10] It is found that in a meta-analysis that the prevalence of depression among people with diabetes was about twice as high as that among those without diabetes Anderson et.al.[11] Therefore, in the treatment of diabetes, it is not enough to consider physical factors alone. Healthy nutrition and regular exercise are important, but we must also pay attention to the emotional factors that are closely related to the quality of life of diabetic patients. Evidencebased behavioral interventions are pressing and needed.

Researchers have advocated over the years a behavioural approach, which involves biofeedback and relaxation training in the treatment of diabetes Fiero et.al. [12]; Mcginnis et.al. [13]. In addition, they have also found the CCH practice can relax the emotions and mood states of schizophrenic patients Fan et.al. [14] and the autistic children Kao et.al. [15]. In recent years, our CCH interventions have further been applied to treat patients with emotion-related diseases, conditions, or disorders. These have included patients with anxiety disorders (Dong, e; al, 1996); Chinese Nasopharyngeal Carcinoma patients experiencing mood state disturbances (Yang, Li, Hong & Kao, 2009), childhood survivors of the 2008 Sichuan-China earthquake with moods disturbance and distress symptoms -- helping reduce PTSD symptoms, cortisol levels and stress, (Zhu, Wang, Kao, Zong, et., al. 2014) as well as breast cancer patients with anxiety and comorbid depression Liu et.al. [16]; Wagner [17].

On the strength of the foregoing clinical studies, the present investigation aimed to test and demonstrate the effectiveness of the CCH training in helping patients with Type II diabetes to reduce their stress, anxiety and mood states.

Method

Measures

Sixteen participants diagnosed with type II diabetes and sixteen healthy control subjects received the CCH treatment, the brush writing of Chinese characters or drawing treatment, which involved drawing of geometric figures with a brush. The Chinese version (STAI; Form Y-1, translated by Ye, 1988) of the State and Trait Anxiety Scale (STAI) Form Y-2, STAI: Speilberger et.al. [18] was employed to measure the anxiety level of the participants. The Profile of Mood States (POMS) Lorr et.al. [19,20] was adopted to evaluate subjective emotional experiences of the normal subjects as well as the clinical patients in six mood states: Depression- Dejection (D), Tension-Anxiety (T), Anger-Hostility (A), Vigour (F), and Confusion-Bewilderment (C).

Design

The 16 normal adults and 16 diabetic patients were randomly assigned to either the CCH practice group or the figure-drawing group with 16 participants in each group. They each performed the respective brush task, writing or drawing, for 45 minutes. The instruments used included a brush made of lamb hair and the rice paper. The writing materials were Chinese characters in a style containing mainly linear strokes and topological properties, while that for drawing consisted of meaningless geometric patterns. The STAI and the POMS were administered to all participants before and after the brush task for the patients as well as the healthy controls.

Results

Based on the State-Anxiety Inventory (S-AI), patients significantly improved on measures of state anxiety (SA) in both the brush writing task (F= 11.97; p=0.004) and the brush drawing task (F=14.08, p=0.002) treatment conditions. In addition, the healthy controls also showed an improved positive effect on SA in both the brush writing (F = 32.02 (p = 0.000) and the brush drawing tasks (F= 14.05, p=0.002). Overall, the patient group’s SAI magnitude reduction is shown greater than that of the healthy controls when the brush writing and the brush drawing tasks are pooled together. (F=5.84, p<0.05?). In addition, The SAI magnitude reduction from the drawing tasks is found to be greater than that of the brush writing task is interesting (F = 5.33; p <0.05?). (Figure 1).

Figure 1: Mean changes in state anxiety scores in practising calligraphy or drawing for diabetes and healthy subjects.

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On the other hand, using the POMS, all participants, including both the patients and the healthy adults, showed a significant reduction in the mood states of tension-anxiety, depresseddejection and confusion-bewilderment after the CCH practice, while a reliable decrease in the states of tension-anxiety, depresseddejection was observed after drawing in both groups. Furthermore, healthy adults, but not the patients, improved in fatigue after the CCH practice, while the patients, but not the healthy adults, improved in fatigue after the brush drawing session (Table 1).

Table 1: Comparisons of scores in POMS before and after treatments (F values).

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Note * P<0.05 **P<0.001

Discussion

This study was designed to investigate the effects of the calligraphy handwriting and drawing on emotional modulation of patients with Type II diabetes and the normal adults. Results have firstly confirmed the stabilizing functions of both tasks, resulting in a relaxation of anxiety. Secondly, improvement in several states of the moods has been found to relate to both types of brushing tasks: Tension-Anxiety, Depression-Dejection, and Confusion- Bewilderment after the CCH practice and Tension-Anxiety and Depression-Dejection after the drawing practice. The contribution of brush writing and brush drawing to the emotional regulation of the diabetes Type II patients is supported in this study. Finally, the findings help to validate the viability of both the calligraphy practice and brush drawing as a new technique as well as an alternative model of behavioural treatment, with special reference to the intervention of emotional and psychosomatic symptoms of diabetes.

These preliminary results are overwhelming and are in line with those similar findings obtained in our other clinical studies on the CCH effects on the moods, anxiety, symptom distress and other emotions that are previously reported.

We have established that Chinese brush handwriting has measurable behavioral, psychological, and emotional effects. We also know that CCH practitioners have enhanced brain functioning, improved cognitive abilities and intellectual skills, and better emotional states. The World Health Organization (WHO) has recognized and endorsed our earlier clinical investigations as having contributed to a major body of theory, knowledge, and a system of treatment Fancourt et.al. [21]. CCH is an effective method for health and therapeutic interventions on cognitive activation, affective-emotion-related anxieties, moods, and distress and as a tool that contributes to the practitioner’s wellbeing and general health. We are pleased that the present research on Type II diabetes has added clinical validation of the CCH intervention for the benefit of human health, wellbeing, and disease treatment.

Funding

Not applicable.

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Thursday, 20 April 2023

Lupine Publishers | Complementary Medicine in Cancer Patients in The View of Health Literacy

 Lupine Publishers | Journal of Complementary & Alternative Medicine


Abstract

While nowadays anticancer therapies had gone through fundamental changes, health care providers must pay attention to the emerging utilization of dietary supplements, functional foods and further complementary and alternative therapies. The appropriate health literacy is a key element in the management of cancer patients’ life too, so it has worthwhile implication in the questions of complementary and anternative therapies. Hence, we wanted to measure the food supplements, functional foods and such agent’s utilization and basic knowledge about them in the Semmelweis University Oncology Center. To our questionnaire 71 patients answered. Due to their knowledge about their antitumor therapies, we divided participants to two groups (N=41 for those, who know their therapies; N=30 for those, who do not know it). However, only 43.9% of those, who know their therapies were precise about it, but grouping was not modified by this data. Tendentious differences were seen between the two groups in the vitamin and/or mineral containing food supplements, herb and/or mushroom containing food supplements, functional foods, special diets, utilization of homeopathy, but significantly more people tried deuterium depleted water in the group of those, who know their therapies. All in all, the type of food supplements etc. seems to be a more prominent factor where from the patient heard about it, in the further sources of information, and in the procurement. Still, health care professionals have a significant role in the good patient education and health literacy, because patients better ask their physician about these products while they mainly purchase them in pharmacies, hence pharmacists have a noteworthy role in the revision of harmful therapies.

Keywords: Oncology; Dietary Supplements; Complementary Medicine; Health Literacy

Introduction

While new and more sophisticated therapies emerged in the treatment of cancer, it should not be forgotten, that the use of complementary and alternative therapies are also increasing. Buckner et al (2018) also studied, why people choose these products. Mainly people try every option to help in themselves, but the real spectrum of the reasons can be much more widespread. All in all, it can be problematic, because some of these agents can cause interactions, while the utilization of such therapies may cause loss of trust in the doctor-patient relationship [1,2]. It is also wellknown, that even supplements are in the category of foods. Hence their effects are not comparable with drugs against cancers [3]. On the other hand, their effects should not be underestimated, as they can be supportive agents in the treatment of a tumor – as well as they can cause life-threating interactions [4].

While the management of life by a patient is an element of health literacy, it seems necessary to improve health literacy of cancer patients [5,6]. This theory has been already proven by Cartwright et al. (2017), as they found negative correlation between health literacy and hospitalizations [7]. Not to mention, there has been present literature about the development of health literacy at cancer patients [8]. For that, in our work we wanted to characterize the health literacy of the Oncology Center of Semmelweis University’s patients about the utilized food supplements, and functional foods, then describe intervention points.

Materials And Methods

Study Design

The study was conducted as guided interviews in the Oncology Center of Semmelweis University (Tömő utca 25-29, Budapest, H-1083, Hungary). Our questionnaire concerned with demographic data, dietary supplements and functional foods. In the study we asked some well-known facts about food supplements. These questions were concerned with safety requirements (if there is any difference between food supplements vs. medical products); differences between manufacturers; the importance of informing someone’s physician about the consumed products; and the risks of food supplement in the light of chemotherapy (or other therpaies). From these data we made a cumulative number, named as “knowledge-point” (maximum = 4 points).

In the questionnaire, to clarify for the patients, an appropriate definition was also given for the above mentioned categories of foods. Furthermore, we asked about the illness, the antitumor therapy and therapies or diets that were not prescribed in the institute. Some pharmaceutical quality products (for instance vitamin C tablets, magnesium tablets) were utilized without a physician’s advice, hence we could not distinguish between some over the counter drugs and food supplements or same products (like foods for special medical purposes), as it was also noticed in the literature [9,10].

Participation in the study was optional and anonymous. The survey was in accordance with the Declaration of Helsinki, approved by the Health Science Council, Scientific and Research Ethics Committee [ETT-TUKEB (Egészségügyi Tudományos Tanács, Tudományos és Kutatásetikai Bizottság) approval number: 31/2016].

Statistical Analysis

Statistical analysis was carried out with Microsoft Excel 2013 (Microsoft Corp., Redmond, USA) and R (R Foundation for Statistical Computing; Austria).

Results

Demographic parameters are shown in (Table 1). It should be mentioned that the survey was mainly conducted in the older generation, but younger patients were also answered to the questions. The youngest patient was 31-year-old women with breast cancer. Most participants lived in cities (83.1%). Patients mainly had higher education. As it can be seen in Table 1. 56.3% had technical school, grammar school or vocational high school education, while 35.2% had a diploma from a university. Rest of the participants had primary school education, no one fulfilled less than primary school. The majority of participants were disability pensioner or retired (66.2%), but more than quartel of the patients were employee (26.8%).

Table 1: Demography.

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As in the question of interactions the current therapies have to be observed, it has been asked from the patients. Mainly people said, they knew their therapies with or without help (41 people; 57.7%), but relevant number of them had no idea about their therapy (30 people; 42.3%). It should be mentioned that significantly more participants from the younger generation knew its therapy. Furthermore, therapies were supervised. Sadly, less than half of the participants (43.9%) know their therapies accurately.

Almost all participants used some kind of vitamin or mineral containing supplement, only two people have not used these kinds of agents. They were from the group of those, who do not know their therapies have not used. In the pattern of where people heard about the vitamin and mineral containing supplement there was no relevant difference, but it is an intriguing difference in the sources of further information between those who knew their therapies. While Figure 1 shows the percentage of every answers, more than 1 answer were acceptable. All in all, 14 from 28 people who do not know their therapies would better use internet, or ask their pharmacist, versus those who knew their therapies. Only 36.6% and 22.0% would use these sources for further information. Furthermore, two more people would ask their naturopath for such information in the group of those, who do not know their therapies. At the questions about vitamin and mineral containing food supplements strangely those, who knew their therapies had slightly less knowledge points (2.97 points) than those, who do not know it (3.03) (Figure 2).

Figure 1: The source of further information about a product The figure shows if a patient needs further data about a product. Numbers are represented in the percentage of every answers.

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Figure 2: Procurement of a food supplements and functional foods. The figure shows the places where pateints purchased the utilized product. Numbers are represented in the percentage of every answers.

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Less people (N=24) answered to the questions about herbs and/or mushroom containing products, but some differences should be highlighted. For herb and mushroom containing food supplements the pattern of answers seems different not only between the two patient groups, but also in the content of food supplement. For instance, in the first question, we asked whom they heard about the therapies. At those people, who know their antitumor therapies, the most important sources were the internet and other advertisements, the second were physicians, pharmacists etc. and the third most important sources were relatives and friends. In the group of people, who do not know their anticancer therapies, the first most important sources were relatives and friends and the second most important were the internet and other advertisements. It should be noticed, that at the question, where these people heard about these herbs and/or mushroom containing products, physician, pharmacist, etc. as well as naturopaths were mentioned only as third most important sources (22%). In the sources of further information, the internet (in the subgroup of others) was the main tool. In the group of people, who do not know their anticancer therapies relatives and friends were also the main sources of information, but in the other group it seems less relevant, while a physician’s advice was prioritized. In these kinds of food supplements pharmacies were the main place where people (in every group) purchased them. An intriguing tendence was seen in the knowledge-points between the group of people who know their antitumor therapies vs, those who do not know it. The mean knowledge-point was almost 15% less in those participants, who do not know their therapies.

Even less people were answered to the questions about functional foods (N=22). People heard about these foods mainly from the internet or other advertisements, but in the group of people, who do not know their anticancer therapies physicians and pharmacists had the same result. If further information would be necessary, people would ask mainly from their physicians, but the second most common sources were pharmacists in the group of people, who now their therapies as well as at those, who do not know Relevant difference from the upper mentioned food supplements is where people purchase them. As these foods are visibly foods, the two groups of participants bought them in food marts.

We asked about further treatments, like diets or nonprescribed medications. From the 41 participants, who know their therapies, 11 utilized some kind of diets. From the 30 people, who do not know their therapies, also 11 utilized some kind of diet. We asked also about homeopathy. Marginal number of participants (N=5) used these medicines, but all of them was in the group of those, who know their anticancer therapies. From these 5 people 2 utilized it because of the cancer, but these two patients also thought that someone should not cease their therapies because of homeopathy, or the utilization of food supplements. All in all, only one, 54-year-old, male participant believed, that he may stop its current therapies (i.e., not only anticancer therapy), because of the utilization of food supplements and/or homeopathy. We also asked about the utilization of deuterium depleted water. Only 7 patients utilized it from the group of participants, who know their therapies, which was significant (p<0,05) by Fisher’s exact test.

Despite of the questions about the supplements, we further asked from people, whether herb or mushroom containing supplements can influence their therapies. In the group of participants, who know their therapies 51.2% thought it may affect their therapies, but these interactions mainly not do serious harm. Twenty-two percent of them thought, that these interactions can cause serious harm, but 26.8% believed, that these products are safe. In the cases of those participants, who do not know their therapies, 46.7% thought, these agents may affect their therapies, but these interactions mainly not do serious harm, 16.7% thought, these interactions can cause serious harm and 36.7% believed that these products are safe.

Discussion

As health literacy raises relevant questions in the whole healthcare systems, the oncology-related health literacy should be also revised and developed, with special attention to complementary and alternative medicines. For that, we wanted to describe the Oncology Center of Semmelweis University’s healthy literature about the utilized food supplements, functional foods, diets and other, non-prescribed therapies in the view of their knowledge about their own antitumor medication.

Limiting factor of our work is the relatively low number of participants, hence statistical analysis may not as punctual. It should be also mentioned that only one cancer center was in the study. On the other hand, as Table 1 shows, the Oncology Center of Semmelweis University provides not only the capital city.

We assessed our data by grouping it to those, who know their therapies and those, who do not know it. Sadly, those, who know their antitumor therapies were also imprecise, and only 43% know it well. On the other hand, we have not seen numerous significant differences between groups. Significantly more younger people know their therapies, which seem to be in good accordance with the well-known history and development of physician-patient relationship [11]. Another significant difference is that those who know their therapies more likely utilized deuterium depleted water. For now, there are clinical trials assessing this complementary agent in therapies, but clinical and preclinical results seem promising [12,13]. On the other hand, it is not clear, why were more utilized at these participants. It is a noteworthy concept, that those, who better know their therapies may try to find more way to help on themselves – while the concept was not really supported by the other complementary therapies (but the small numbers may bias the results).

In the last decades, internet become a main source of information, as well as a main point, where people can purchase products [14]. Even so, physicians are the most important sources of information, and pharmacies are the most important places to purchase these products. Two exceptions should be highlighted: in the group of those, who do not know their therapies, the main source of information was relatives and family members at the herb and/or mushroom containing products; and functional foods were mainly purchased from food marts. In the second highlighted case it should be mentioned that these products seem to be foods, and easy to mix with normal foods.

On the other hand, physicians have a noteworthy opportunity to inform patients about food supplements or functional foods, etc. regardless of how patients know their therapies. This can be crucial in the case of herb or mushroom containing products because these agents’ interaction spectrum is less studied than vitamin or mineral containing supplements. However patient education is not the duty of only the physicians, and the literature has many examples that they may need help in this work [15, 16]. The alteration in the education of pharmacists and other healthcare specialists are reliable opportunities in these questions, as pharmaceutical training for example contains lectures about herbs and mushrooms.

Another intervention points are the pharmacies. They are one of the last healthcare specialists before the patient may use a product. It seems an important point to check the food supplements and such products. Also it can be necessary for the patient to know their therapies – which means, 42.3% of the participants posed to some kind of pharmaceutical risk, and a further 43.9% had a minor risk, as they know some information about their therapies. While questioning a patient can lengthen the dispensing, pharmacists may provide better information to patients than other places [17].

All in all, food supplements, functional foods, special diets, etc. are common in the complementary and alternative therapies of patients in an oncology center. While these products and products are easily available, health care professionals have to describe intervention points and find tools to inform patients about the risks and benefits.

Conflict of Interest:

The authors declare that they have no conflict of interest.

Funding

We would like to thank for the ”Together for the Local Communities” application, provided by Hungaropharma Zrt.

Acknowledgement

We would like to thank Hungaropharma Zrt. for its support in the “Together for Local Communities” application and to dr. Dorina Ali, dr. Szonja Bóta dr. Diána Simon for the help at the questionnaires. Dietary supplements and supplemented diets

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Saturday, 4 March 2023

Lupine Publishers | A Reflection on Yoga, Acupuncture and Medicine

 Lupine Publishers | Journal of Complementary & Alternative Medicine


Introduction

In the 20th Century a great effort has been made both to prove that yoga and acupuncture (i.e., Chinese medicine) can be used for health-related purposes and to discover the functional mechanisms of both systems. From the Western point of view, when both yoga and Chinese medicine became popular as a Complementary and Alternative Medicine (CAM) a resistance became perceptible that led to regulation of CAM (CAMDOC Alliance, 2010). The main issue is that Western and Eastern medicine have a different approach to both health and treatment of illness.

In case of yoga, it has to be stated that it was not conceived as a medical system, but as a system for the discovery of the ultimate goal of humans – Self-realization. Thus, its methods – though there are a great number of yoga traditions – are directed to this aim. Nevertheless, hatha yoga has a strong emphasis on health and has a wonderful spectrum of procedures for arriving at a health status that enables intensive pursuing of the said ultimate goal manifested as samadhi that follows from the cessation of the activities of chitta – the substance of mind/mindfield. The result stated in Patanjali Yoga sutra (PYS) is:

1.3. Tada Drishtu Swarunele Vasthanabh || 3 ||

Tada Drashtuh Svaroope Avasthanam that is: the seer then rests in his unmodified state Usharbudh [21]. Rishi Vyasa in his commentary to verse I.1 of PYS declares that yoga is samadhi Usharbudh, et.al, [16,21]. Whilst Patanjala yoga relies on the training related to chitta, Hatha yoga offers a wide range of “doable” processes starting with shatkarmas, asanas and pranayama, but Hathayoga Pradipika Akers [1] and Gheranda Samhita Digambarji, et.al, [4] offer training also for pratyahara, dharana, dhyana and samadhi. As pointed out by Avalon [2,3] Tantrik yoga defines and works with nadis, chakras and their energies. The nadis (energy cum information pathways) are defined in a tentative way, usually –at least in case of the main 14 nadis – by their start and endpoints and also by giving their relative position to Sushumna – the main nadi. It is also defined that the number of petals in the yantras of chakras (graphic composition symbolically indicating the role of the chakra), refer to the number of nadis stemming from them Khanna [9] Kundalini, one of the main issues kundalini of Tantra Yoga experienced also a doubting approach Sanella [17]; Dongart [5]. Nevertheless, the PubMed at the time of writing this paper has 54 entries on this subject.

The concept of chakras is linked also to the sankhya model of the world that uses tattvas for modelling the “construction” of the perceptible world (cf Ashurbudh 1986, 23-39). Thus, each chakra is assigned a tattva – from earth to akasha. Usually, yoga mentions 7 chakras, but the ajna chakra (6th) and sahasrara (7th) do not relate to the five tattvas. Much research went to get a measurable proof of nadis and chakras (cf. Motoyama1981), but they were not truly accepted by Western science. Treatises like Gheranda samhita Digambarji et.al, [4] and Satkarma sangrahah Harshe[10] devote attention also to purifying the nadis (Gheranda sanhita 5.34-37, p.30) and making them passable for pranas Yogeshwaranand[23].

The Sarva upanishad nicely defines the koshas – functional units of humans, thought the described functional units would not be easily understood by medicine: “The aggregate of the six sheaths, which are the products of food, is called the Annamaya-kosha, alimentary sheath. When the fourteen kinds of Vayus beginning with the Prana, are in the alimentary sheath, then it is spoken of as the Pranamaya-kosha, vesture of the vital airs. When the Atman united with these two sheaths performs, by means of the four organs beginning with the mind, the functions of desire, etc., which have for their objects sound and the rest, then it (this state) is called the Manomaya-kosha, mental sheath. When the soul shines being united with these three sheaths, and cognisant of the differences and non-differences thereof then it is called the Vijnanamaya-kosha, sheath of intelligence. When these four sheaths remain in their own cause which is Knowledge (Brahman), in the same way as the latent Banyan tree remains in the Banyan seed, then it is spoken of as the Anandamaya-kosha, causal frame of the Soul. When it dwells in the body, as the seat of the idea of pleasure and pain, then it is the Karta, agent”.

To make the studied yoga system even more complex, it works also with marmas Vasishtha Samhita [22] and bindus Gitananda [8], which – to the Western mind appear also as model based and “abstract”. Contemporary efforts to make yogic concepts mapped into modern physical or other scientific frames did not produced reliable results, but Newcombe [15] has shown the vast cultural areas in which yoga got acculturated in the West and thus paving the way for adapting some of its concepts and methods also in health care.

Yoga and health

As the spectrum of possible application of various yoga techniques in health management is vast, here only a couple of examples can be given. There are 2352 publications at PubMed regarding the health effect of meditation. The way, how meditation is defined, though differ. There are 3338 studies at the same search portal on yoga and health. Again, the methodologies differ. So, it is difficult to quantify the contribution of specific techniques or yogic “structural units” like marmas, nadis, chakras or koshas to health benefit.

Meridians of the Chinese medicine, as they were somewhat better “measurable”, due to the fact that they were intended for medical usage and thus precisely described/situated, became a “bridge” in making the “invisible” measurable. Romodanov et.al, [16] were amongst the first to use thermo-vision to make meridians visible by stimulating their master points. Gach and Marco already in 1981 tried to develop yoga practices that stimulate meridians. In trying to explain the work of nadis, Maxwell [12] wrote: „While it is difficult to imagine how subtle gap junction mechanisms could be studied in humans, a recent Chinese study has demonstrated an increase in the expression of a particular gap junction protein (connexin 43) at an acupuncture point in rats using acupuncture stimulation “.

At present there is an increasing number of works that try to quantify the impact of yoga practices on health by measuring the skin resistance at specific meridian points like Ghosh K [7,14], but it still falls short of demonstrating that working with elements of the „yogic anatomy/physiology“has a quantifiable and measurable impact on health and wellbeing. Further, the units used for the impact assessment do not make the results well comparable to result of classic medical processes. Nevertheless, in yogic training the trainee has very specific perceptions of the work of all the mentioned structural elements that traditional yoga defined Lu K´uan Yü [11] and it can be hoped that there will come a time, when science will have the tools for discovering the “secrets” of yogic model of humans and of the universe.

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Thursday, 5 January 2023

Lupine Publishers | Life Course In HEARTS: Enhancing Telehealth Resilience and Mindfulness Intervention in Older Adults Experiencing Abuse and Trauma-A Conceptualization

 Lupine Publishers | Journal of Complementary & Alternative Medicine


Introduction

Advances in research and evidence-based practice improve the prevention and treatment of diseases, but the marginalized seems to be left behind [1]. The purpose of this paper is to conceptualize a telehealth intervention aimed to improve the health and health span of older adults. More particularly, we articulate the conceptual framework underlying our intervention, Telehealth Resilience Mindfulness (TRM) Intervention, which will be delivered via text messaging (for those who have phones or smartphones), video conferencing such as Zoom (for those with internet connectivity), or in-person (when it is practical) to older adults to enhance HEARTS (health, experiences of abuse and trauma, resilience, technology use, and social support). Healthcare is a human right a resource to mitigate disparities in healthspan, defined as the portion of life spent in good health [2]-enriching opportunities if there is collaboration in interdisciplinary education, research, and practice [1,3]. We propose a telehealth intervention as a resource for older adults in mitigating disparities in healthspan. A telehealth intervention is defined as the use of information and communication technologies for health that encompasses positive emotions, optimism, and cognitive appraisal [4-7]. Telehealth interventions have the potential to reduce the psychobiological exposure to abuse and trauma and their health-related consequences as technology provides a safe, timely, and flexible space for the target population compared with traditional face-to-face approaches [7]. Additionally, interventions for the prevention and reduction of abuse among women [8-11] had positive health and social outcomes. Some telehealth interventions were included in these reviews and showed mixed results [7,12]. For these reasons, we are exploring and conceptualizing opportunities for enhancing the feasibility and efficacy of the telehealth resilience-mindfulness intervention in older adults.

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Our overall objective is to expand causal pathways underlying successful aging using PROMIS health indicators predictive modeling to examine how the HEARTS outcomes by environment interaction in telehealth resilience mindfulness intervention impact healthspan [13]. The telehealth resilience mindfulness intervention could improve health outcomes and increase healthspan delivering it by text messaging, videoconferencing (e.g., Zoom), or in-person (when possible). Once conceptualized, we will test specifically the feasibility and efficacy of the HEARTS telehealth resilience and mindfulness intervention by linking objective tests with subjective tests of health variables and the biobehavioral attributes of resilience in a future study. We will hypothesize that the intervention promotes better health outcomes, openness in sharing experience of abuse and trauma, enhance resilience, and social support. Our long-term goal is to establish a research infrastructure for interprofessional collaboration that expands the evidence-based biobehavioral telehealth resilience interventions and to improve healthspan (the portion of life spent in good health) by linking biobehavioral attributes of resilience with technology use, and social support through predictive modeling technique. The establishment of an infrastructure for interdisciplinary collaboration globally will expand the biobehavioral evidencebased telehealth resilience mindfulness intervention increasing healthspan.

Today’s telehealth nursing care approaches can serve a wide range of populations and make a significant contribution to the efficacy and delivery of health care. However, there is a lack of research data to support the readiness for adopting the use of telehealth interventions among a wide variety of clinical situations, with diverse patients, and in a variety of settings. By examining the feasibility and efficacy of HEARTS Telehealth Resilience Mindfulness (TRM) Intervention among older adults, we will explore older adults’ readiness for adopting the use of technologybased interventions to improve their health and healthspan. For a future study, we ascend to De Los Reyes’s [14] suggestion that a theoretical model framework (Range of Possible Changes [RPC] Model) to conceptualize, examine, and classify the available evidence for interventions. We will adopt the RPC Model to theorydriven hypotheses and conduct a mixed-methods design to test whether the telehealth resilience mindfulness intervention may or may not change biopsychological constructs for older adults who have experienced abuse and trauma.

Significance

The older adult population is growing faster than all younger age groups as their healthspan (a portion of life spent in good health) is decreasing. Globally, one in six people of 60 years and older experienced abuse in their homes, community, and institutional settings every year, and the annual loss by victims of financial abuse is estimated to be at least $36.5 billion [15]. The experience of abuse robs older adults of their dignity, security, healthspan, and in some cases, their lives, leaving a stubborn imprint as they age [13,15-17]. Elder abuse and history of abuse include physical, emotional, sexual, economic, and neglect [15,18]. The risks of leaving the experience of abuse and its consequences unmitigated are devastating to the survivor (personally), family (interpersonally), and community [19].

Preliminary studies suggest that experiencing abuse exacerbates the risks for health indicators, resilience, social support, and technology use a psychosocial impact on the healthspan of older adults [20,21]. It is imperative to determine the socio-behavioral mechanisms that account for older adult’s health disparities related to their experiences of abuse, resilience, technology use, and social support. Social determinants of health are rooted in a system of structuring opportunity and assigning value based on the social interpretation of how young the person is, and it unfairly disadvantages individuals and communities, sapping the strength of persons through the waste of human resources [3,22]. We have accepted that during this pandemic, that distancing, quarantines, and social isolation, are perfect deterrents for the COVID-19 virus to spread, however, it is a risky practice in caring for older adults. The socio-behavioral interventions such as social support [23], and self-efficacy and behavioral therapies [24] throughout the lifecourse are known but certain forms of interventions that enhance biobehavioral attributes of resilience facilitating reappraisal and promote social support preserving a sense of purpose in the face of abuse are not well developed [6,25]. There is a critical need to explore the biobehavioral processes associated with telehealth resilience and mindfulness intervention using objective tests and subjective tests [12,25-26].

Conceptual Framework

The Life Course Health Development (LCHD) framework [27,28] provides the theoretical foundation of our conceptualization of health and health trajectory of our target population in our research - the older adults with experience of abuse and trauma. The LCHD constitutes comprehensive biological, social, and environmental aspects of health that influence health outcomes later in life [27]. The conceptual foundation of LCHD came when Elder [29] developed an integrated ecological systems model examining changing life trajectories by leveraging contextual effects that accumulate over time and influence the individual’s trajectory. There are six key tenets of the LCHD framework, all predicated by health: 1) health is a set of capacities that develops over time (older adults); 2) health constantly develops by interactions between biology (health), and environment (social support, technology use); 3) health involves a complex, non-linear system over several dimensions, phases, and levels; 4) health is responsive to the social structuring and timing of ecological experiences (experience of abuse); 5) health has an evolving process that uses resilience and plasticity to adapt to changing ecological contexts; and 6) health is responsive to the timing and synchronization of the level of ecological pathways (personal, interpersonal, community, and society), with molecular to biological to social and cultural functions [28]. We are using these tenets with a focus on the ecological pathways and integrating health, experience of abuse, resilience, technology use, and social support.

Literature Review

The socio-behavioral interventions in abuse throughout the life course are known but certain forms of interventions that enhance biobehavioral attributes of resilience facilitating reappraisal and promote mindfulness preserving a sense of purpose in the face of abuse are not well developed [6,25,30]. There is a critical need to explore the changes and biobehavioral processes associated with telehealth resilience-mindfulness intervention that has biopsychosocial underpinnings of resilience [6].

The Health of Older Adults

Despite improvements in current approaches to an aging population, the health of older adults is not keeping up with increasing longevity [31,32]. Older adults contribute to society in diverse ways - through their family, community, and society. The extent of their contributions to society depends on their health. One major challenge in assessing the health of older adults is the sheer diversity of health and functional states they experience that are loosely associated with chronological age [15]. Diversity, inequity, stereotyping, and other social determinants of health must be addressed to transform a comprehensive global public health response to an actively aging world population. The need to transform misaligned health systems with the older adults’ needs, clearly and convincingly requires redefinition and reconceptualization. Adding healthspan and continuous improvement of health care systems is crucial. Our proposed study attempts at redefining the health of older adults more broadly and diversely including physical function, anxiety, depression, fatigue, sleep disturbance and sleep-related impairments, the ability to participate in social roles and activities, pain interference, and pain intensity.

In our HEARTS study [20], we operationally defined health as that of the determinants stated in the PROMIS-29 questionnaire [33,34], which specifically pertains to physical function, anxiety, depression, fatigue, sleep disturbance, sleep-related impairment, ability to participate in social roles and activities, pain interference, and pain intensity. The experience of abuse refers to the different types of abuse older adults experience, physical, emotional, sexual, economic, and neglect [18,35]. Finally, resilience in our study is operationally defined as “personal qualities that enable one to thrive in the face of adversity” [36, p. 76]. Results showed that all the PROMIS health subscales are significantly correlated with each other [20,21]. Resilience is correlated with anxiety, depression, and pain intensity, such that higher resilience corresponds to lower anxiety, depression, and pain intensity [20,21]. Additionally, we find that suspicion of abuse has significant correlations with depression, pain intensity, and resilience [20,21]. Namely, higher depression and pain intensity correspond to higher older adults’ abuse suspicion, while higher resilience corresponds to lower older adults’ abuse suspicion [20,21]. Technology use or without technology use impacts the experience of abuse and social support [37]. We also have to be careful that technology could have a bias because they are created by humans, of humans, and for humans.

Detailed correlation results from regression models indicated that above and beyond demographic features, resilience had a significant prediction of anxiety [β = −0.46, p = .014] and depression [β = −0.54, p = .008]. Our findings on the significant negative relationship between older adults’ resilience and their depression and anxiety are consistent with other related studies exploring correlates of older adults’ resilience [11,38]. Additionally, our findings on the significant predictive effect of resilience on depression and anxiety imply the protective properties of resilience on depression and anxiety among older adults [38,39]. Hence, our findings concur with the conceptualization of resilience as that of a multidimensional construct comprising of individual characteristics such as attitudes and behaviors that facilitate adaptive coping despite adversities [40]. In a review of studies exploring the characteristics of the resilience of older adults, MacLeod et al. [41] reported that adaptive coping styles contribute to building resilience and thereby, reduce high levels of anxiety and depression.

Experience of Abuse

Elder abuse refers to acts whereby a trusted person (a family member, close friend, or caregiver) creates a risk of harm to an older adult [15]. The legal definition of older adult investment in and return on investment in adding health to years in older adult abuse varies by state and country but is defined as a person who is or may be mistreated and who, because of age, disability, or both, is unable to protect themselves [42]. The World Health Organization [15] reported that older adult abuse is now recognized internationally as a public health problem. As a result, older adults’ health as a pervasive societal concern requires the attention of health care systems, social welfare agencies, policymakers, researchers, educators, and the general public [42]. With a global increase in the older adult population, older adult abuse is expected to become an even more pressing problem, affecting millions of individuals worldwide. Older adult abuse is associated with devastating health consequences and societal costs. The global population of older persons will triple from 672 million in 2010 to 1.9 billion in 2050 [43]. It is becoming increasingly important to focus on policies and practices that support and enhance the wellbeing of older adults. For many, older adult abuse is cause for alarm, albeit their voices are drowned by poverty, disability, and cultural stereotypes. It is extremely difficult to quantify the extent of abuse, neglect, and exploitation because many cases go undetected and unreported [42].

A study of victimization among older adults and the effects of two resilience factors (i.e., sense of coherence [SOC] and social support) reported a negative association between victimization and health status [18]. In this study [18], victimization was associated with two resilience factors, SOC and social support. Additionally, SOC had a positive correlation with health status and social support moderated the association, i.e.., participants without social support had lower health scores [18]. Lack of social support and low SOC was found to be associated with high victimization with a suggestion that both resilience factors (SOC and social support) should become targets for future interventions [18].

In another study about the effects of abuse on health, Hui and Constantino [44] analyzed the data from the 2007 Behavioral Risk Factor Surveillance System (BRFSS) with a sample size of n=19,102 from the states of Hawaii, Virginia, and West Virginia. In this study, about 16.9% had experience with intimate partner violence (IPV). They also found that those who had experience with IPV by their sex partner had more mentally unhealthy days in a month compared with persons who have no experience of IPV [44]). Additionally, persons who had unwanted sex had at least 72 unhealthy days in a year, negatively impacting their healthspan [44]. These results appear somewhat consistent with the findings from the World Health Organization multi-country sample that found women who reported IPV at least once in their lifetime also reported significantly more emotional distress, suicidal thoughts, and suicidal attempts, compared to women who did not experience IPV [45].

The Resilience of Older Adults

Resilience is the human regenerative capacity that maintains health and function in the face of loss, disability, or disease [46] or bending without breaking, transforming failure to growth and challenges into opportunities, but it is fungible and expendable [47]. Hoare [25] suggested that the human attribute of resilience has a lengthy history, with positive adaptation as a marker [48]. The construct of resilience is found in theories of motivation and self-efficacy [49]. Recently, resilience is considered an attribute that supports health outcomes for those who had been exposed to trauma, environmental hazards, or poor caregiving [50]. Resilience throughout the life course enhances the ability to recover from adversity, thrive with a sustained purpose, and grow in a world of trauma, change, and chronic illness [46]. Resilience allows older adults to adapt to the wear and tear of aging while coping with problems and crises in ways that leave them feeling stronger and wiser than they would have been if they had not encountered those problems [46]. Furthermore, resilience is seen as both a process and an outcome [48] while others consider resilience a trait or inborn capability [48] or as a more fluid attribute that comes into play as one equilibrates after trials and tribulations of life [51].

Anderson et al. [52] conducted a mixed-method study to examine the resilience and growth in the aftermath of violent experience. The study elicited that spirituality, religious beliefs, and social support are crucial in the recovery process by giving them strengths and life purpose [52]. Survivors from her interviews display resilience by evaluating and adjusting mindsets, understanding life is not easy, and achieving greater life purposes by helping other survivors and sharing their own stories. In another study, the sense of coherence (SOC) as a factor of resilience had a positive correlation with health status and social support as well as moderate the association between lack of social support and lower health scores [18]. Lack of social support and low SOC was also found to be associated with high victimization with a suggestion that both SOC and social support as factors of resilience should become targets for future interventions [18].

The issue of whether the resilience phenomenon stands on its own or is the same as longsuffering, endurance, or positive emotionality [53,54] needs further study. Literature seems to suggest that resilience is fungible and can be “diminished,” “replenished,” or “regained” after adversity [55]. Despite its definition and conceptualization variance, resilience is possessed throughout the lifespan but varies in levels, therefore, assessable, and measurable [53,56-57]. Among resilience intervention studies, cognitive reframing can alter negative perceptions and mastery development can enhance a sense of achievement [25] in older adults. Furthermore, collaborations among researchers promise new resilience-enhancing interventions [6].

Proposed Research Design

We will use a mixed-method sequential, transformative design to implement and test our proposed intervention, Telehealth Resilience Mindfulness (TRM) intervention. This design features an advocacy lens in which the quantitative and qualitative components of the study vary in order and priority [58]. The quantitative part will utilize a quasi-experimental method. This design will enable us to determine the efficacy of HEARTS telehealth resilience and mindfulness (TRM) Intervention based on objective and subjective outcomes. The objective outcomes will be measures through blood pressure readings, heart rate, and respiratory rate, while the subjective outcomes are measured through their health (PROMIS), the experience of abuse, resilience, and social support. The HEARTS telehealth resilience mindfulness intervention will be mainly delivered by text messaging. A baseline data will be gathered before the start and after the conclusion of the intervention. For comparison, there will be two treatment groups in this study: The Telehealth Resilience Mindfulness (TRM) and the Wait-List Group (WLG). The phenomenological qualitative design of the study will focus on the lived experiences of participants on HEARTS Telehealth Resilience Mindfulness Intervention.

Hearts Telehealth Resilience Mindfulness (HEARTS TRM) Intervention

We anticipate that the TRM intervention could result in an observable effect on emotional and physical engagement, attention to the cognitive organization [5,6]. Furthermore, Emezue and Bloom [5] suggest that the more communication technologies (computers or smartphones) are used, the more likely the older adult will reject abusive and disrespectful treatment. Policymakers and program planners should consider the potential implications of information technology access relating to survivors of abuse. Constantino et al. [10] found that survivors felt that disclosing their experience was easier and safer through a computer than face-to-face with a clinician or any “interested” person, and that advice from a computer or phone was acceptable and accessible. However, participants may feel skeptical of a computer’s ability to give empathy, emotional support, or meaningful feedback [20]. For this reason, in this prospective project, we will explore the feasibility of TRM delivered by text messaging to enhance resilience and mindfulness to survivors. Emezue and Bloom [5] report that evidence shows most survivors of abuse prefer the practicality and confidentiality of technology-enabled interventions and guided online support as opposed to in-person individual or group meetings, making this telehealth an opportunity in enhancing resilience and mindfulness. Hoare [25] focused on cognitive reframing and reappraisal, showing that reports of reappraisal and reframing tend to be more flexible and have better social outcomes. The figure shows our proposed mixed-method study.

Figure 1: Proposed Mixed-Method Study in Telehealth Resilience Mindfulness Intervention.

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Description of the HEARTS Telehealth Resilience Mindfulness (TRM) Intervention

The HEARTS Telehealth Resilience Mindfulness (TRM) Intervention is comprised of eight weekly sessions, primarily delivered by text messaging. The focus is on the improvement of resilience through the development of mindfulness skills. Below further describe the details of each weekly session.

Week 1

Daily application of one or more of the following mindfulness exercises: Sit comfortably erect on a chair and feet flat on the floor. Open your eyes and drop your gaze to the floor beneath your feet and breathe. Remove as many distractions as you can but keep focus first on the internal sensations from your body. Notice your limbs, neck, shoulders, and breathe, then your abdomen, diaphragm, and chest. Notice your thoughts and feelings. Imagine you are in front of your door, waiting for your visitors to arrive. They came, and you greeted them with love, kindness, and compassion. Then focus on the external sensations that are delivered to your 5 senses. -sight, smell or its absence, taste, or its absence, hearing or its absence, and touch-cooler or warm temperature. Then integrate these 2 (internal and external) sensations you have. Thirty 30 minutes. Weekly journaling of lessons learned and the flow of thoughts and feelings. Weekly phone or TM (Text Messages) check-in.

Week 2

Exercises-Movement for Week 2 includes the following: (1) Bend your thumb across the palm as far as you can. Do this 20 times. (2) Place palm flat on the table. Spread them apart and bring them close together. Do this 20 times. (3) Pick up a pencil or a pen. Roll it between the thumb and each finger. Do this 20 times [59]. (4) Setup: Begin sitting in an upright position. Movement: gently squeeze your shoulder blades together, relax, and then repeat 20 times. (5) Setup: Begin in a standing upright position in the center of a doorway. Movement: With your elbow bent, place your hand on the side of the doorway. Take a small step forward and slightly rotate your body until you feel a stretch in the front of your shoulder. Hold this position for 3 seconds and repeat it 10 times. Imagine your agility, flexibility, and concentration [60]. Total of 25-30 minutes. Weekly journaling of lessons learned and the flow of thoughts and feelings. Weekly phone or TM check-in.

Week 3

Daily application of one or more of the following mindfulness exercises: Setup in an upright position with your feet flat on the floor. Movement: Gently draw your chin in, while keeping your eyes fixed on something in front of you. Do not look down or bend your neck forward, being mindful of feelings, and thoughts without judging (10 minutes). Observe yourself (15 minutes) by focusing on the upper portion of your body, your chest, heart, and lungs, and diaphragm-observe their function [60]. Total of 25 minutes. Weekly journaling of lessons learned from these exercises. Weekly phone or TM check-in.

Week 4

Unscramble these words and put them in a correct sentence on a clean sheet of writing paper: (1) “almond my cream favorite chocolate is ice”; (2) “crackers bed should never one eat”; (3) “the swipe machine card your through”; (4) “picked of peppers Piper peck Peter a pickled”; (5) “Senate vetoed tax the the both the and House bill”; and (6) “the 200th States marked birthday 1976 of the United” [61]. No judgment but focus, concentrate and relax. Weekly journaling of lessons learned from these exercises. Weekly phone or TM check-in.

Week 5

Daily application of the following mindfulness exercises: Being mindful of your feelings. Close your eyes and imagine you are a leaf on a stream who aims never to be swept to the banks-always focus and concentrate to float in the middle of the stream no matter where the wind or the waves from the rocks toss you until you get to the river and then to the sea and travel to the ocean. The wind and waves could be the trials and tribulations that you meet in your journey to life’s stream, river, sea, and ocean; you can mention them but do not focus on them-they are only distractions. Focus on your journey and the positive emotions, sensations, memories, and resilience. 20 minutes. Weekly journaling of lessons learned from this exercise-- awareness of one’s values, greater resilience, reduce autopilot, and less reactive. Weekly journaling of lessons learned from these exercises. Weekly phone or TM check-in.

Week 6

Answer each question with a one-word response on a writing paper. The number of letters provided is a clue to the answer: (1) A sound of laughter- 2 letters; (2) To harm or cause pain-4 letters; (3) Equals 60 seconds- 6 letters; (4) Equals 60 minute- 4 letters; (5) What you walk on- 5 letters; (6) Between sunset and sunrise- 5 letters; ( 7) What many people live in -5 letters; (8) opposite of man-5 letters; (9) not this one, but-one- 4 letters; and (10) an eating utensil- 4 letters [61]. Weekly journaling of lessons learned from these exercises, following directions, focus, and concentration. Weekly phone or TM check-in.

Week 7

The following are the activities for Week 7: (1) Listen to the news show for 5-10 minutes and write down your summary of the most important information. (2) Read a paragraph in a magazine or newspaper or online and write down a summary of what you read. (3) Provide directions to your friend from your airport to your place house. Weekly journaling of lessons learned from these exercises, following directions, focus, and concentration. Weekly phone or TM check-in.

Week 8

Daily application of one or more of the following mindfulness exercises: Write down specific directions you would like to five to a friend, from your local church or airport to your house—improved focus, give/following directions, ability to face challenges, and cognitive regulation. Weekly journaling of lessons learned from a video: Cognitive regulation. Weekly phone or TM check-in.

The mindfulness exercises and lessons described above were adapted from Erin Commendatore, a mindfulness webinar interventionist at the University of Pittsburgh Mindfulness Series, from March to April 2021. The resiliency sessions were adapted from works on the resilience of Feder et al. [6], Hoare [25], and Reyes et al. [62].

The answers to the Week 4 exercises (unscramble the words to form into a sentence) are the following: 1) My favorite ice cream is chocolate almond. 2) One should never eat crackers in bed. 3) Please swipe your machine card through. 4) Peter Piper picked a peck of pickled peppers. 5) The Senate vetoed both the tax and the House bill. 6) 1976 marked the 200th birthday of the United States. Here are answers to Week 6- One-word response to 10 questions: 1) HA, 2) HURT, 3) MINUTE, 4) HOUR, 5) FLOOR, 6) NIGHT, 7) HOUSE, 8) WOMAN, 9) THAT, and 10) FORK.

Instruments for Evaluation

A brochure will be distributed to communities where potential participants gather. Below are the descriptions of each of the instruments for evaluation that will be used:

Sociodemographic Data Questionnaire (SDQ)

The SDQ will be used at baseline only to document age, race, education, employment, religion, and income. The SDQ can be completed in 3-5 minutes.

Health

We will use the PROMIS (Patient-Reported Outcomes Measurement Information System) version 1.0 short form [33,34] to assess anxiety to determine health status including, four items on physical function, anxiety, anger, depression, fatigue, sleep disturbance, ability to participate in social roles and activities, pain interference, and pain intensity [33,34]. Testing among over 20,000 individuals from the U.S. general population has resulted in individual item calibrations that enable one to generate a T-score (mean = 50; standard deviation = 10). The health subscale can be completed in 4-5 minutes.

Elder Abuse and Lifetime Experiences

We will use the Responding to Elder Abuse in Geriatric care - Self-administered (REAGERA-S) [35] will assess elder abuse (e.g., has anyone threatened to harm you? and have you experienced physical abuse before or after you were 18 years old?). Space will be provided to check the type of abuse the participant has experienced: emotional, physical, sexual, or economic. The sensitivity of the instrument, for lifetime abuse, is 71.9% (95% CI 53.3-86.3) and specificity 92.3% (95% CI 79.1-98.4). For current abuse, the sensitivity is 87.5% (95% CI 61.7-98.5) and specificity is 92.3% (95% CI 79.1-98.4). REAGERA-S can be completed in 3-5 minutes.

Resilience

The Connor-Davidson Resilience Scale 10-item, CD-RISC-10 [63] will be used to measure psychological resilience. The CD-RISC-10 comprises 10 items, and each item on the scale is rated on a 5-point Likert scale from 0 (not true) to 4 (true nearly all the time). The total score ranges from 0 to 40, with higher total scores indicating greater resilience. The scale demonstrated good construct validity and internal consistency (α = .85) during the development of the scale [63]. The CD-RISC-10 also had a good Cronbach’s alpha level of .85 [63]. The CD-RISC-10 can be completed in 5¬-7 minutes.

Social Support

The Interpersonal Support Evaluation List (ISEL) is the instrument we will use to measure social support. ISEL was originally developed for a standard adult population [64,65]. The scale measures interpersonal support in four dimensions: information support, spending free time together, instrumental support, and appreciation - self-esteem. The type of coping strategy depends primarily on informational support received, and finally, how a person responds to stress is highly associated with received social support [66]. Reliability and validity studies of the ISEL using adult samples reported internal reliability (alpha coefficient) for the ISEL ranging from 0.88 to 0.90, and between 0.70 and 0.82 for appraisal, 0.62 and 0.73 for self-esteem, 0.73 and 0.78 for belonging, and 0.73 and 0.81 for tangible support [65,67-69]. The ISEL can be completed in 57 minutes.

Feasibility and Acceptability of the Intervention. An interview guide will be used to explore the feasibility and acceptability of the intervention and the quality of its administration and accessibility of the HEARTS Telehealth Resilience and Mindfulness Intervention among participants. The interview can be completed in 25-35 minutes.

Conclusions

Systemic factors in healthcare and justice services increase or decrease healthspan (a portion of life spent in good health) throughout the life course. Lifecourse Health Development [27,28] is a theory that integrates biological, socioeconomic, justice, and environmental infrastructure. This conceptualized TRM practice change can be delivered in-person by text messaging or by video conferencing (i.e., Zoom). The rationale is to span the digital, biological, socioeconomic, justice, and environmental infrastructure divide between the service providers Strategies that will be used to implement the practice change (TRM) are community-based participatory research and practice, that emphasize collaborating, consulting, and where ethics, role and role responsibility and accountability, communication, and teamwork competencies in community participants’ engagement are paramount [70].

We are aware that sometimes during our life course we have been marginalized. Marginalization is a process through which certain individuals experience multiple social determinants concurrently placing them in sections and margins, by rejecting one’s culture, race, age, gender, or sexual orientation by the dominant host population [1]. Legarde [71] identifies an approach to empowerment and equality as judging people by their capability to do the things they value. This approach to empowerment facilitates the ability to participate in one’s community and contribute to sustainability in health outcomes. Failed attempts at integration lead to marginalization expressed in three main outcomes: the creation of margins, living between cultures, and the creation of vulnerabilities. The creation of margins is a process of creating boundaries, sections (intersectionality), and peripheralized by approximation (not proximation) of the individual, group, or population. Age and poverty create margins, sections, and vulnerabilities [71].

The second outcome of marginalization is living between cultures leading to incomplete integration where the individual relinquishes characteristics of the parent culture to connect with the dominant society and fails in both [1]. In the process of living between cultures, the person lives on the periphery on the verge of exclusion, and the intersection of multiple ways of distancing. The third and last outcome of marginalization is the creation of vulnerabilities. Vulnerabilities are a state of being exposed to, and unprepared to fight or flee from health, people, and environment’s damaging circumstances that pose a physical, psychological, biological, social, and economic threat to the individual, group, or population. Age disparities are an example of the creation of vulnerabilities. Globally, older adults make up 60% of the living on less than a dollar a day, locked out of leadership positions, underutilized, underpaid, under-appreciated, stressed, abused, and traumatized [18]. The cumulative outcome of these three themes of marginalization is toxic stress that leads to maladaptive coping behaviors, poor self-esteem, lack of self-efficacy, cognitive dissonance, and increased incidence of substance abuse, posttraumatic stress, and suicide [3].

The strength of the evidence guiding the change (HEARTS Telehealth Resilience Mindfulness [TRM] Intervention) in practice comes from the Range of Possible Changes (RPC) Model that guides the theory of change in intervention. We are aware that technology may have some bias, prejudice, and stereotypes because they are made by, for, and of humans. The stakeholders that will influence and participate in the change in practice are observable in institutions’ ethics, role, communication, and teamwork help and not hinder, catapult and not shackle and cutting away obstacles and barriers to true human flourishing. The evaluation strategies will assess the impact of change that are embodied in HEARTS (health, experiences of abuse and trauma, resilience, technology use, and social support) in a mixed-methods strategy where qualitative data are quantified and quantified data are qualified, in the development of a telehealth resilience mindfulness intervention.

Conflict of Interest Statement

No conflict of interest has been declared by the authors.

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