Showing posts with label Research & Reviews. Show all posts
Showing posts with label Research & Reviews. Show all posts

Thursday, 6 September 2018

Pediatric Gastroesophageal Reflux Disease: (RRHOAJ)-Lupine Publishers



Pediatric Gastroesophageal Reflux Disease by Margarida Silva Fonseca in Research and Reviews on Healthcare: Open Access Journal (RRHOAJ) in Lupine Publishers

Gastroesophageal reflux disease is the result of persistent Gastroesophageal reflux associated with symptoms and/or complications. It is the most prevalent esophageal pathology in pediatric population and it is one of the most common causes for medical consultations. The identification of extra esophageal manifestations and associated alarm signals allows an appropriate treatment, an early identification of esophageal mucosal injury and prevention of complications.

We Take Care: A Punk Point of View to the Brand New Psychiatry: (RRHOAJ)-Lupine Publishers

We Take Care: A Punk Point of View to the Brand New Psychiatry by Collettivo Bisacco in Research and Reviews on Healthcare: Open Access Journal (RRHOAJ) in Lupine Publishers

The Collettivo BISACCO is a mixed group of users, stakeholders and workers that cooperate in the Mental Health Service of Turin, Italy. The project started 5 years ago with a social art performance in Sebrenica- Bosnia. After we had collaboration with many institutions and international cultural events. Now with partnership of Associazione Insieme (a family association) and Gruppo Famiglia (the network of all family oriented practices) we started a new project. We promote a users oriented analysis of scientific report on the main topics of psychiatric studies. Now we are building up a group who shares scientific information’s to promote a debate in the clinical world. This is a starting paper based on some of the discussion we had. We use a collective name because we refuse using patient’s activities and direct expressed opinion to enhance personal careers. The name BISACCO is referred to a Turin psychiatrist who had an important role in the closure of psychiatric hospital in Turin and now is the name of the service (a little bit rehab, a little bit clubhouses and something more) where we meet.


Diabetes Mellitus: A Multifactor Approach: (RRHOAJ)-Lupine Publishers

Diabetes Mellitus: A Multifactor Approach by Amanda Caroline Cardoso in Research and Reviews on Healthcare: Open Access Journal (RRHOAJ) in Lupine Publishers

Diabetes Mellitus (DM) is a chronic non-communicable disease characterized by chronic hyperglycemia due to an impaired glucose metabolism [1-3]. It can occur by an autoimmune process in which there is destruction of the beta cells of the pancreas, leading to deficiency of insulin secretion characterizing the DM type I, which affects children and adolescents, may be due to a combination of insulin resistance and the inadequate compensatory response to insulin secretion, predominant in the DM type II, affecting adults , when glucose intolerance occurs during the second or third trimester of gestation, it is characterized gestational DM (GDM), and other types of diabetes are reported in the literature, such as those caused by genetic defects of beta cell function, disorders genetics in the action of insulin, exocrine pancreatic diseases, endocrinopathies, drug induced or other age chemical infections, viral infections, unusual immunological forms, and genetic syndromes associated with diabetes [4,5].





Friday, 31 August 2018

Circadian Disruption, Sleep Loss, and Low-Grade Inflammation: (RRHOAJ)-Lupine Publishers

Circadian Disruption, Sleep Loss, and Low-Grade Inflammation by RĂ¼diger Hardeland in Research and Reviews on Healthcare: Open Access Journal in Lupine Publishers

Circadian rhythmicity is a fundamental property of the majority of organisms, including bacteria, unicellular eukaryotes, fungi, plants and animals. It is generated by cellular oscillators and may have evolved to cope with adverse phases in the cycle of a day that bear the risk of damage by radiation and reactive metabolites, such as free radicals. In a complex organism like the human, the circadian system is composed of numerous, internally communicating, oscillators including a coordinating master clock, the suprachiasmatic nucleus (SCN) [1]. It provides a program for structuring countless physiological functions in a sophisticated temporal pattern that optimizes the alignment of processes and also the anticipation of regularly expectable changes, such as an approaching time of arousal and locomotor activity, of food intake and even social interactions.



The Electric Potential of the Female Body Liquids and the Effectiveness of Cloning: (RRHOAJ)-Lupine Publishers

The Electric Potential of the Female Body Liquids and the Effectiveness of Cloning by Yuri Pivovarenko in Research and Reviews on Healthcare: Open Access Journal in Lupine Publishers

It was previously shown that the electric potential of biological liquids of the female body correlated with the stages of the menstrual cycle: these liquids have a negative potential at the stage of ovulation, but the positive potential on the phases before and after ovulation. It was also shown that the electric potential of the water determines its surface tension, as well as its ability to hydrate the polysaccharides. On the basis of obtained results it is concluded that the electrical potential of the body liquids of women, and is the surface tension and the ability to hydrate the polysaccharides of these liquids, can be cyclically varied during the menstrual cycle. It is demonstrated that the use of these ratios allows influencing the processes of reproduction and increasing the efficiency of cloning.


Nanoemulgel Innovative Approach for Topical Gel Based Formulation: (RRHOAJ)-Lupine Publishers

Nanoemulgel Innovative Approach for Topical Gel Based Formulation by
Bhupendra G Prajapati in Research and Reviews on Healthcare: Open Access Journal in Lupine Publishers 

The lipophilic nature of majority of newly developed drugs has resulting in poor bioavailability, and pharmacokinetic variations. The goal of this evaluation is to evaluate and report the current potential and future scope of nanoemulgel formulation for becoming an effective delivery system for poorly water-soluble drugs. Nanoemulgel consist two different systems in which drug containing nanoemulsionis incorporated into a gel base. The fusion of these two systems makes this formulation advantageous in several ways. Lipophilic drugs can be easily incorporated and the skin permeability of the incorporated drugs can be enhanced in several folds due to the finely distributed oil droplets in gel phase. Simultaneously, it can be targeted more specifically to the site of action and can avoid first pass metabolism and relieve the user from gastric/systemic incompatibilities. The nanoemulgel drug delivery system is a formulation related intervention to improve drug absorption and therapeutic profile of lipophilic drugs. An increasing trend in nanoemulgel use in recent years has been noticed because of the better acceptability of the preparation to the patients due to their non-greasy, convenience spreadability, and easy applicability and good therapeutic and safety profile. Despite having few limitations, nanoemulgel formulation can be considered as potential and promising candidates for topical delivery of lipophilic drugs in the future.