Splendid achievements have been made in management of
disease through invention of drugs over past decade. The present conventional
drug delivery systems often have side-effects and complications due to their
wide distribution throughout the body fluids. The localization of drug action
in injured tissue is a promising way to solve this problem. The objective of
drug targeting isto achieve a desired pharmacological response at a selected
site without undesirable interaction at other sites. This is especially important
in cancer chemotherapy and rheumatoid arthritis treatment. Recently invention
of drugs has been generated by various drug delivery systems like microspheres,
liposomes, noisomes, nanocapsules and nanoparticles. Among all colloidal drug carriers’
nanoparticles are gaining more popularity because of their stability, easy
preparation, for achieving reduced toxicity, for increased drug efficacy &
site targeted action. Nanoparticulation is a very useful strategy towards
targeted drug delivery and also for enhancement of bioavailability of low
soluble drugs. In this article nanoparticles preparation methods and their
biomedical applications were discussed in detail.
http://www.lupinepublishers.com/drug-designing-journal/abstracts/a-review-on-biomedical-applications-of-polymeric-nanoparticles.ID.000140.php
http://www.lupinepublishers.com/drug-designing-journal/pdf/DDIPIJ.MS.ID.000140.pdf
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