Saturday 29 September 2018

Diet, Obesity and Diabetes: Archives of Diabetes & Obesity - Lupine Publishers

Obesity and diabetes have become a very important global problem. In developed countries the incidence of both seems to have stabilised probably due to greater awareness and better education. Weight reduction in obese subjects with diabetes can be achieved by bariatric surgery and often results in remission of diabetes, hypertension and dyslipidaemia but at a cost of mortality and morbidity. Dietary intervention until recently has been relatively unsuccessful. Recently however, structured, low calorie diet with nurse/dietician support in a general practice setting has shown promise. Successful drug therapy to aid weight reduction remains elusive.

Evaluation of the Prevalence of Gestational Diabetes Using Fasting Blood Glucose and Glycated Heamoglobin in Yenagoa Metropolis: ADO - Lupine Publishers

There is understanding that most pregnant women with gestational diabetes mellitus stands the risk of having adverse obstetric and perinatal outcome. The need for an early detection and effective management of this problem with a view to ensure better maternal and fetal protection was the driving thrust for this study. Through the application of spectrophotometric methods employing enzymatic and non-enzymatic systems, the concentration of fasting blood glucose (FBG) and glycated Haemoglobin (HbA1c) were determined in 2nd and 3rd trimester pregnant women and compared with non-pregnant women. Data were analysed using student’s t-test with the aid of Graph pad Prism (R) software version 6.10 at p<0.05 values considered statistically significant. Result reveals that 11% of pregnant women investigated had gestational diabetes mellitus in Yenagoa metropolis. Our findings elucidate the danger of gestational diabetes mellitus, its prevalence and the need to allow for effective proactive intervention program regarding screening and management and in addition highlight areas requiring further research.

Friday 28 September 2018

Lymph Node Blood Vessels: Exit Route for Systemic Dissemination of Cancer (CTBM) -Lupinepublishers

Lymph Node Blood Vessels: Exit Route for Systemic  Dissemination of Cancer (CTBM) -Lupinepublishers

There are reports about the existence of meningeal lymphatic vessels in human and nonhuman primates (mormoset monkeys) and feasibility of noninvasively imaging and mapping them in vivo with high-resolution, clinical MRI. On T2-FLAIR and T1-weighted black-blood imaging, lymphatic vessels enhance with graduator, a gadolinium-based contrast agent with high propensity to extravasate across a permeable capillary endothelial barrier, but not with gadofosveset, a blood-pool contrast agent. 

A present and global threat called Extended-Spectrum Beta-lactamases (ESBLs) (CTBM) -Lupinepublishers

A present and global threat called Extended-Spectrum  Beta-lactamases (ESBLs) (CTBM) -Lupinepublishers

The urinary tract infection (UTI) is a common cause of antibiotic prescription in general medicine. The main etiological agents of UTIs are the Enterobacteria, that account for about 70 to 80% of the isolated microorganisms in the laboratory routine. In most cases,the empirical treatment is initiated, without the request of the urine culture, which can result in therapeutic failures and worsening of
the disease due to the development of microbial resistance.

Antifungal Properties of Some Essential Oils against Saccharomyces cerevisiae (CTBM)- Lupinepublishers

Antifungal Properties of Some Essential Oils against  Saccharomyces cerevisiae (CTBM)- Lupinepublishers

To evaluate the antifungal activity of four essential oils against Saccharomyces cerevisiae in vitro, four commercial essential oils extracted from Thymus vulgaris, Echinacea Angustifolia, Rosmarinus officinali and
Salvia officinalis were tested at three different concentrations (10, 50 or 100 ppm) for their antimicrobial activity against Saccharomyces cerevisiae using well diffusion method. S.cerevisiae was least susceptible to the essential oils. The diameter of zoneinhibition ranged between 0 and 3 mm.  E. angustifolia, and R. officinalis oils appeared to be the most active, while T.vulgaris and S. officinalis oils exhibited most weak antifungal activity against S. cerevisiae. These findings increase the possibility of exploiting these essential oils as a safe alternative natural preservative.