Clinical Evaluation of Herbal Active Enriched Shampoo in Anti Dandruff Treatment (TRSD) - Lupine Publishers

Clinical Evaluation of Herbal Active Enriched Shampoo in Anti Dandruff Treatment by Sudhir Sawarkar in Theranostics of Respiratory & Skin Diseases - Lupine Publishers

The human scalp is susceptible to microbial build-up if not thoroughly and frequently washed with the appropriate cleansing agents such as shampoos. Natural oils are presented in our scalp and it called as a sebum and it is a fuel/food for the dandruff-causing microbe. Malassezia feeds off these oils, breaking it down into by products, including oleic acid; formation of oleic acid is a starting/ kick point of dandruff. Approximately 50% people in the world sensitive to the oleic acid and affected by the dandruff. Overall clinical study results revealed that usage of tested anti-dandruff shampoo is effective and significantly reduce the dandruff fungi in scalp. Efficacy was analyzed with changes in the intensity of hair fall over 6 weeks from baseline to treatment visits using Visual Analogue Scale (VAS). The average response of Visual Analogue Scale for visit1 and visit 5 was 6.287 and 0.350 respectively. The average response/changes of Visual Analogue Scale score for Visit1 is 100.00 and Visit 2 having the score of 74.360; Visit 3 having the 47.924, Visit 4 having the score of 19.453 and Visit 5 was having the score of 5.567. It is concluded that there is statistically significant difference between the average response of Visual Analogue Score (VAS) between Visit 1 and Visit 5 which is indicative of remarkable improvement of dandruff over a period of 6 weeks. The tea tree oil in the formula act as a carrier to carry the actives in to the deeper part of the scalp; synergistic combination of natural and synthetic chemicals helps to control the dandruff. Overall study confirmed that the synergistic combination of synthetic anti-dandruff and natural ingredients plays a crucial role in control the anti-fungal, anti-inflammatory and local immune stimulatory actions.

https://www.lupinepublishers.com/trsd/abstracts/TRSD.MS.ID.000105.php

https://www.lupinepublishers.com/trsd/pdf/TRSD.MS.ID.000105.pdf

https://www.lupinepublishers.com/trsd/fulltext/TRSD.MS.ID.000105.php

Evaluation of the Anti-Inflammatory Activity of Semi -Purified Glycoside Extracted from the Leaves of Plumeriarubra (Kalachuchi): (RRHOAJ)-Lupine Publishers

Evaluation of the Anti-Inflammatory Activity of Semi-Purified Glycoside Extracted from the Leaves of Plumeriarubra(Kalachuchi) by Renato I Dalmacio in Research and Reviews on Healthcare: Open Access Journal in Lupine Publishers


The researchers focused on skin inflammation. An inflammation is a biological response of the body aiming to remove the harmful stimuli that affects a part of our body. Based on visual observation, the ancients characterized inflammation by five cardinal signs; heat (calor) is caused by the increased movement of blood through dilated vessels into the environmentally cooled extremities, also resulting on the increased redness (rubor), swelling (tumor) is the result of increased passage of fluid from dilated and permeable blood vessels into the surrounding tissues, infiltration of cells into the damaged area, and in prolonged inflammatory responses deposition of connective tissue, pain (dolor) is due to the direct effects of mediators, either from initial damage or that resulting from the inflammatory response itself, and the stretching of sensory nerves due to oedema and loss of function (functiolaesa) refers to either simple loss of mobility in a joint. (Punchard N.A., Whelan C.J., Adcock I., 2004)[1-3].

http://www.lupinepublishers.com/rrhoaj/pdf/RRHOAJ.MS.ID.000104.pdf 
http://www.lupinepublishers.com/rrhoaj/abstracts/RRHOAJ.MS.ID.000104.php 
http://www.lupinepublishers.com/rrhoaj/fulltext/RRHOAJ.MS.ID.000104.php

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