Journal of Chemical Sciences-Lupine Publishers

Biological Studies, Synthesis, Structural, Spectral Characterization and Co-Ordinate Mn (II), Fe (II), Zn (II) (II) Complexes Containing 2-Hydroxy-1- Naphthaldehydeand n,n’-Dimethyl-1,3-Propanediamine in Kadhiravan S in An archive of organic and inorganic chemical sciences in Lupine Publishers

A new Manganese (II), Iron (II), Zinc (II), complex, has been and characterized by elemental analysis, UV-Vis, FT-IR and Binding of this Mn (II), Fe (II), Zn (II) complex with calf thymus DNA was investigated by UV-Visible absorption, fluorescence spectroscopy techniques. The intrinsic binding constants Kb of complex with CT-DNA, BSA obtained from UV-Vis absorption studies were 1.75X1 05,1.98X105and2.38X105M-1.

Metal chelates are capable to tolerate their antitumor effects by binding to DNA. DNA binding alters the replication of DNA by inhibiting the growth of the tumor cells, which is the basis of designing new and more effective antitumor drugs. Among the DNA binding modes, intercalation is the most significant one because it always leads to cellular degradation [1]. Intercalation is the insertion of small molecules between stacked base pairs of the double helix structure of DNA. It leads to subsequent disruption of base stacking in the double helix by creating interference in hydrogen bonding or vander Waals interactions and results in the destabilization of double helix conformation of DNA. Thus, the consequence of intercalation include inhibition of transcription, prevention of DNA synthesis, structural changes of DNA, disturbances in cellular processes and finally cell death. More consideration has been paid on DNA intercalation, since the other DNA binding need more investigation for structure-function relationship. The groove binders along with intercalations can also be used for the treatment of bacterial, fungal infections and cancer.

https://lupinepublishers.com/chemistry-journal/fulltext/biological-studies-synthesis-structural-spectral-characterization-and-co-ordinate-mn-ii-fe-ii-zn-ii-ii-complexes-containing-2-hydroxy-1-naphthaldehydeand.ID.000140.php

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Si-Psa Tape with the Addition of Dolomite (AOICS) - Lupine Publishers

Si-Psa Tape with the Addition of Dolomite (AOICS) - Lupine Publishers

It is well known that tapes on the silicone pressure-sensitive adhesives base are high quality products used for special applications. Due to the excellent performance characteristics such as high adhesion, cohesion and tack, while high chemical and environmental conditions resistance, the choice of the layer protecting the adhesive film is a big problem. Due to this, expensive fluoridated films are used as protective layers. In order to reduce costs, a suitable bending of the protective layer was introduced (limitations of the contact surface of the adhesive film with a protective layer) which reduces the protection of the adhesive film. The introduction of dolomite particles into the adhesive film is intended to facilitate the removal of the protective layer, while maintaining the level of protection at the level of expensive films.

https://www.lupinepublishers.com/chemistry-journal/fulltext/si-pSA-tape-with-the-addition-of-dolomite.ID.000121.php

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Multi-Component Synthesis of Novel Diazoles: their Characterization and Biological Evaluation: (AOICS) - Lupine Publishers

Multi-Component Synthesis of Novel Diazoles: their Characterization and Biological Evaluation by Shad HA, Hussain A, Shahzad K, Abeeha, Hussain G, Khan ZI, Ahmad K, Alam MM and Ilyas M in Archive of organic and inorganic chemical sciences(AOICS) in Lupine Publishers

A new series of imidazoles were synthesized by multiple component system through condensation reaction of benzil, substituted aldehydes, substituted anilines and ammonium acetate. Glacial acetic acid was used as solvent. The bonding behavior and structure of the prepared compounds have been deduced from infra red spectroscopy, conduction method, and CHN analysis data. The synthesized imidazoles have been examined for in-vitro antibacterial properties. The results of these studies have shown that all compounds exhibited fair to major antibacterial activity against one or more bacterial strains.

http://www.lupinepublishers.com/aoics/abstracts/AOICS.MS.ID.000107.php
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