Friday 31 August 2018

Circadian Disruption, Sleep Loss, and Low-Grade Inflammation: (RRHOAJ)-Lupine Publishers

Circadian Disruption, Sleep Loss, and Low-Grade Inflammation by RĂ¼diger Hardeland in Research and Reviews on Healthcare: Open Access Journal in Lupine Publishers

Circadian rhythmicity is a fundamental property of the majority of organisms, including bacteria, unicellular eukaryotes, fungi, plants and animals. It is generated by cellular oscillators and may have evolved to cope with adverse phases in the cycle of a day that bear the risk of damage by radiation and reactive metabolites, such as free radicals. In a complex organism like the human, the circadian system is composed of numerous, internally communicating, oscillators including a coordinating master clock, the suprachiasmatic nucleus (SCN) [1]. It provides a program for structuring countless physiological functions in a sophisticated temporal pattern that optimizes the alignment of processes and also the anticipation of regularly expectable changes, such as an approaching time of arousal and locomotor activity, of food intake and even social interactions.

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