Nonmosaic Klinefelter Syndrome Successful Conception after TESE/ICSI: A case report: (OAJRSD)- Lupine Publishers

Nonmosaic Klinefelter Syndrome Successful Conception after TESE/ICSI: A case report by Vasilios Tanos in Open Access Journal of Reproductive System and Sexual Disorders in Lupine Publishers

Klinefelter syndrome patients are mostly clinically azoospermic, and before the era of TESE, were unable to father genetically their own offspring. Nonmosaic Klinefelter [NMK] patients have chances of fatherhood once sperm is harvested from the epididymal seminiferous tubules and further injected in the ovarian cytoplasm. We report a case of 36y old NMK patient, treated for 3 months with supportive and hormonal medication achieving a pregnancy after TESE/ICSI. This is the first published case of successful conception in a couple with a nonmosaic Klinefelter father in Egypt using TESE/ICSI. Review of the literature for any advantages of mTESE over TESE and conception demonstrated higher pregnancy rates by TESE although the sperm retrieval rate was similar in both techniques.

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