Wednesday, 3 October 2018

The Specific Role of Periodontal Disease in Lung Cancer Pathogenesis: (MADOHC) - Lupine Publishers


Abstract

It has been proposed that poor oral hygiene, especially in high risk patients could be a predatory factor for respiratory diseases. Oral cavity that coincides with trachea could be a natural gate for colonization by respiratory pathogens. Dental plaque can be colonized by those that have been inhaled from the oro pharynx cavity to the upper airways and then can approach the lower airway and adhere to the bronchial or alveolar epithelium [1,2]. Periodontal Disease (PD) has been associated with chronic lung diseases, such as Chronic Obstructive Pulmonary Disease (COPD) [3,4]. It has also been recorded that pulmonary function in COPD patient’s decreases with increasing Clinical Attachment Loss (CAL), and an association between poor oral hygiene and COPD was recorded after controlling for potential confounders, such as gender, age, smoking andsocio-economic level [5]. The mentioned findings were in accordance with those that carried out from previous casecontrol and prospective studies [6-10].



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