A Comparison Study for Chances of Reduction in Cardiovascular Risk by Draksharishta in Induced Diabetic Condition: (DDIPIJ) - Lupine Publishers

A Comparison Study for Chances of Reduction in Cardiovascular Risk by Draksharishta in Induced Diabetic Condition by Subhajit Ghosh, Dr PN Murthy and Dr H Joshi in Drug Designing & Intellectual Properties International Journal (DDIPIJ) in Lupine Publishers

In this study was to evaluate the effect of Draksharishta-T and Draksharishta -M prepared by traditional and modern methods respectively and Dabur Draksharishta and comparison between them on fasting blood glucose and serum lipid profile in alloxan induced diabetic rats. Oral administration of Draksharishta-T, Draksharishta-M and Dabur Draksharishta (2ml/kg p.o.) for 21 days caused a significant decrease in fasting blood glucose (FBG) and showed significant rise in blood glutathione level (GSH) in diabetic rats. Glibenclamide was used as a standard anti diabetic drug (10 mg/kg, p.o). These preparations also caused significant reduction in serum cholesterol, LDL and triglycerides and showed significant rise in serum HDL level in diabetic albino rats. Thus all these preparations were able to maintain the tested parameters near to the normal level significantly.

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