Role of Combinatorial, Medicinal & Biological Chemistry in Drug Discovery Development: An Introduction: (AOICS) - Lupine Publishers

Role of Combinatorial, Medicinal & Biological Chemistry in Drug Discovery Development: An Introduction by Prakash Prajapat in Archive of organic and inorganic chemical sciences (AOICS) in Lupine Publishers 

Combinatorial chemistry, a new approach for greatly reducing the time for the discovery of newer organic motifs, has been developed over the last few years. Combinatorial chemistry (Figure 1) is a technique for creating huge numbers of biologically potent motif and their hybrids, then rapidly screening them for desirable properties 1. Almost pharmaceutical and agrochemical industries uses this strategy because of the potential for immense reducing in time and cost, and several drug candidates presently in clinical trials are products of this methodology. Drug discovery process (Figure 2 & 3) is long, time and money intensive process [1].

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