Process for Preparation of Vitamin C and Method for Determination of Vitamin C in Tablets by Krishnasarma pathy in Surgery & Case Studies: Open Access Journal in Lupine Publishers
Procedure for calcium ascorbate (VITAMIN-C) includes such technological
steps as reaction of ascorbic acid on calcium
carbonate in water. In recent years, the determination of vitamin C has
become an important subject in the field of biochemistry and
commercial foods. This is because vitamin C plays an important role in
maintaining human health. Due to the importance of vitamin
C in human beings, the quantitative analysis of vitamin C has gained a
significant increase in several areas of analytical chemistry
such as pharmaceutical and food applications. There are numerous methods
for the determination of vitamin C in a variety of natural
samples, biological fluids and pharmaceutical formulations. The
prepartaion method and methods for the determination of vitamin
C are spectrophotometric methods and non-spectrophotometric methods
(Arya and Mahajan, 1997). For non-spectrophotometric
methods are such as high-performance liquid chromatography (HPLC),
titration, enzymatic method and fluorometry (Arya, Mahajan
and Jain, 2000). Direct spectrophotometry also has been applied to
determine the vitamin C content in soft drinks, fruit juices, and
cordials after correction for background absorption in the UV region.
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