Wednesday 26 September 2018

Varied Presentation of Unusual Soft Tissue Lesions- A Case Series: (RRHOAJ)-Lupine Publishers

Varied Presentation of Unusual Soft Tissue Lesions- A Case Series by Kafil Akhtar in Research and Reviews on Healthcare: Open Access Journal in Lupine Publishers

Malignant chest wall tumors are broadly classified into eight main diagnostic categories: muscular, vascular, fibrous and fibrohistiocytic, peripheral nerve, osseous and cartilaginous, adipose, hematologic and cutaneous. Some other malignant chest wall tumors that do not fit well in any of such category are synovial sarcoma and ewing’s sarcoma. Sarcomas of soft tissues, particularly those from the deep sites of the extremities raise a problem of diagnosis and treatment. Hemangiopericytoma (HPC) is a rare vascular tumor, and is most controversial, because earlier it was thought to represent a neoplasm of the pericytes of Zimmerman. Histiocytic sarcomas, including malignant fibrous histiocytoma (MFH), represent a group of neoplasms with an unpredictable course and for which treatment varies widely. Pleomorphic malignant fibrous histiocytoma (MFH) which is also known as undifferentiated high-grade pleomorphic sarcoma according to the latest World Health Organization classification is a diagnosis of exclusion. Myxoid liposarcoma (LS) is the most common subtype of liposarcoma and occurs predominantly in the extremities. Different cytogenetic features and their underlying molecular alterations define distinct entities among LS. Myxoid LS has a strong and specific association of the (12;16). Inflammatory fibrosarcoma, commonly referred to as inflammatory myofibroblastic tumor (IMT) has become as part of a spectrum of inflammatory myofibroblastic proliferation. It is potentially locally aggressive tumor of the mesentery of children and young adults. Immunohistochemistry plays an important role to distinguish different types of soft tissue tumors with similar morphology.

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