Friday 28 September 2018

Progresses in Gene Therapy of Neurodegenerative Disorders: Online Journal of Neurology and Brain Disorders - Lupine Publishers







Gene therapy is a technique that uses genes to treat or prevent diseases. Gene therapy to the brain faces other difficulties in addition to the general issues one faces with gene therapy. A major limiting factor for the delivery of gene to the brain is the blood brain barrier (BBB), which most gene expression vectors can not cross naturally. However, recent advances in gene transfer technology have led to promises for delivery of therapeutic genes to brain. In this small review we shall make a discussion on the recent developments of gene therapies for some important neurodegenerative disorders.

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