One Step Synthesis of Coumarinfrom Cinnamaldehyde via Cinnamic Acid Intermediate: (AOICS) - Lupine Publishers

One Step Synthesis of Coumarinfrom Cinnamaldehyde via Cinnamic Acid Intermediate by Made Sudarma in Archives of organic and inorganic chemical sciences in Lupine Publishers

The purpose of this study was to develop an efficient method for the synthesis of pharmacologically interesting coumarin (1-benzopyran-2-one) from readily accessed natural products, in particular cinnamaldehyde. One step methodology for the synthesis of coumarin has been developed from cinnamaldehyde. A coumarin was synthesized smoothly via addition of chloro sulfonic acid to cinnamaldehyde. All the products have been confirmed by Thin Layer Chromatography and Gas Chromatography Mass Spectromatry analysis data.

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