Biomechanical Engineering Analysis of Glaucoma Micro Stent Implant with Check Valve for Intraocular Pressure Reduction (IOP) by Finite Element Method (FEM) by Ö Karaçalı in Open Access Journal of Biomedical Engineering and Biosciences (OAJBEB) in Lupine Publishers
Abstract
Biomechanical factors affect the
design model of glaucoma micro stent (GMS) geometry, material and shape in
correcting treatment of high intraocular pressure (IOP). The goal of this
research was to characterize the biomechanics of the GMS using computational
finite element method. In this research, the model for nano-composite materials
will be investigated for analyzing the material behavior of the GMS with check
valve used in the intraocular fluid evacuation system which is not made until
now to control the intraocular pressure. It has not been reported about what
impacts on GMS with check valve design and material selection to ensure
discharge of ocular fluid in intraocular pressure (IOP), ensuring fluid flow
continuity. Finite element Analysis simulation methodology for realization of
accurate structural and aqueous humor (AH) behavior micro model during this analysis
provided valuable results of useful data of GMS material behavior that are time
consuming and expensive to determine otherwise. The check valve provided a
control mechanism for AH pressure to regulate the IOP. For this reason,
material deformation von-Mises and fluid flow behaviors model was developed. To
achieve these, finite element analysis were employed to calculate compressive
stresses and equivalent von-Mises stress criteria as well as the analysis by
the strength of material’s experimental procedure in laboratory conditions. A
finite element analysis (FEA) of GMS under very low cyclic loading conditions
is presented. The results of modeling were verified with experimental data for
biocompatible and biodegradable GMS from nano-composite material. This research
provided a data set for preventing glaucoma disease and improving intraocular
tension by new design of GMS.
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