A Computational Simulation of Bladder Cancer Growth by Chia Jung Chan, Tin-Kan Hung, and Chih-Han Chang in Open Access Journal of Biomedical Engineering and Biosciences (OAJBEB) in Lupine Publishers
Abstract
A three-dimensional (3D) simulation
is established for bladder cancer development. Distribution of cancer cells is
obtained by using a Monte Carlo procedure. The tumor blocks are meshed with
uniform hexahedral microelements. Each element is assessed on its cancer growth
probability (CGPi) during a time interval. The CGPi value is related to the
growth of tumors. In this study, the exponential growth of tumors is
considered. Factors associated with the immune system, medication, and other
cell conditions were not yet included. The 3D computational modeling is
anticipated to develop patient-specific simulation towards clinical management.
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