Numerical Investigation of Graphene-Gold Spr- Based Biosensor: (OAJBEB) - Lupine Publishers

Numerical Investigation of Graphene-Gold Spr- Based Biosensor by Saeideh Jafari, Jafar Mostafavi Amjad, Ramin Mohammadkhani and Peyman Jahanshahi in Open Access Journal of Biomedical Engineering and Biosciences (OAJBEB) in Lupine Publishers

Abstract

This short study is aimed to investigate the graphene-gold surface plasmon resonance (SPR)-based biosensor by optimizing the graphene and gold layers respectively. Gold (Au) is used as a noble-metal material whereas graphene is used to avoid Au from oxidation and enhance the reflectance intensity of biosensor as well as increase molecular absorbance on the sensor surface for improving sensitivity. Numerical analysis is performed using finite-element method (FEM) by comparing the sensing performance such as reflectance intensity that explains the sensor sensitivity. The measurements are presented with various graphene thin film thicknesses in 3nm, 5nm, and 6nm with 800nm operating wavelength, and then considered the different gold thicknesses (10nm to 70nm). The proposed sensor shows that the five-layer graphene-40nm thick gold SPR-based sensor gave better performance with narrower plasmonic spectrum line width. The obtained results also indicate that the graphene-gold SPR-based sensor is suitable for medical diagnostics in immunoassays.

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