Coumarin and Coumarin-related compounds are major source of interest for
many of medicinal chemist to explore its various pharmacological
potentials especially bis-coumarin for their anticoagulant activity. A
number of reports have appeared in the literature on the enhancement of
bioactivity of bis heterocyclic compounds over simple heterocyclic
compounds. Biscoumarin are very well known and possess better biological
activities like anticoagulant, anti oxidant, antimicrobial activity,
anti cancerous and analgesic activity than the parent nuclei. Hence,
realizing the importance of biscoumarin, we thought to summarize the
synthesis of bis-coumarins under solvent-free conditions in this review.
No comments:
Post a Comment
Note: only a member of this blog may post a comment.